What should be included in the labeling when adding more than 10% of the labeled volume of a bag?

When adding more than 10% of the labeled volume of a bag, it is crucial to include the total volume on the labeling, which reflects the overall amount of the solution in the bag after the addition. This practice ensures that anyone handling or administering the medication is fully aware of the final volume, which is vital for accurate dosing and patient safety. If the total volume is not clearly indicated, it could lead to incorrect medication administration and potential harm to the patient.

Including just the original volume or the additional volume alone would not provide a complete and clear picture of the content, potentially resulting in confusion or dosage errors. Specifying the weight of the contents in grams, while useful in some contexts, does not replace the need for a clear understanding of the volume, particularly in IV compounding where volume is critically relevant for infusion rates and overall fluid management.